Design and Implementation of Bioinformatic Tools to Analyze Protein Sequences

Abstract

Proteins are one of the important fundamental units of all living cells. Proteins have a large number of functions within all the living organisms. Some of the important functions performed with the help of proteins such as DNA replication, catalysis of metabolic reactions, transportation of molecules from one place to another etc... There are 20 different types of amino acids that can be combined to make a protein sequence. Integrins are cell adhesion molecules that mediate cell-cell, cellextracellular matrix, and cell-pathogen interaction. They play crucial roles in leukocyte trafficking, migration, immunological synapse formation, costimulation, and phagocytosis. The studies of integrin molecule structure and function helps in better understanding the various pathological processes such as chronic inflammation, thrombosis and cancer metastasis. The study can help the researchers to discover a new drug to cure all these.To analyze the protein sequence with respect to primary structure, secondary structure and tertiary structure it needs the help of various bioinformatic tools. Most of these tools are web based tools and it requires internet connection to work with them. There are lot of challenges in maintaining proper internet connection all the time. So, developing an offline tool using high performance programming language like julia will be helpful for researchers to work with them at any time irrespective of internet connection.