Comparison of Efficay of Who Ors Solution with Hypoosmolar Solution in Pediartric Unit I of Services Hospital Lahore

Abstract

OBJECTIVES: To compare the resolution of hypoosmolar with WHO-ORS in children with acute watery diarrhea (AWD).

Place and Methods: A double-blind, randomized controlled study was performed at the Pediatrics Unit I Services Hospital, Lahore for the period of six months from July 2017 to December 2017 After verbal agreement 300 children between 2 months and 12 years matched the clinical case definition of AWD. The other half was randomized to receive a hypoosmolar ORS solution for one hundred fifty children while WHO received the standard ORS solution. Children with third degree severe dehydration, malnourishment, systemic infections and intravenous fluids received children according to Gomez classification were discarded from the study. Information about the effect of each treatment method was monitored for 6 hours. The effectiveness of the ORS and the development of hyponatremia are the outcome measures. The efficacy was measured as the need for vomiting, vomiting and unprogrammed intravenous fluids at the rate of sweating. The data were analyzed with SPSS 13 and Chi square test was applied to the outcome measures.