Anti-Anemic Activity of Hydro-Alcoholic Extract fruit of Physalis minima in Phenylhydrazine Induced Anemic Rats

Abstract

The aim of this research was to evaluate the anti-anemic activity in hydro-alcoholic extract of fruits of Physalis minima in phenylhydrazine induced anemic rats. Phenylhydrazine (40mg/kg) was given intraperitoneally in rats for two days to induce anemia. The animal were divided into 5 groups of 6 animal each. Group 1 was known as normal control group, Group 2 was known as anemic control group, Group 3 was known as standard reference control group given with Vit. B₁₂, Group 4 was known as test control-I given with 100mg/kg of hydro-alcoholic extract of fruits of Physalis minima, Group 5 was known as test control-II given with 200mg/kg of hydro-alcoholic extract of fruits of Physalis minima. All the test drugs were given for 28 days through oral route once in a day. On 29^th day blood was taken out through tail puncture and was subjected to the determination of RBC, Hb and percentage Hematocrit. Both the hydro-alcoholic fruit extract of Physalis minima and Vit. B₁₂ significantly increase the HB, RBC & percentage Hematocrit level which shows that Physalis minima fruit exhibits the anti-anemic activity.