Application of Vilsmeier Haack Reagent in the Synthesis of Heterocyclic Compounds

Abstract

The present article is a review highlighting the utility of Vilsmeier-Haack reagent in the synthesis of heterocyclic compounds. The synthesis of heterocyclic compounds are achieved by reactivity of Vilsmeier Haack reagent towards activated methyl and methylene moiety of the substrate leading to its cyclization or the sequential transformation involving the use of nitrogen and oxygen of substrate as nucleophile under vilsmeier condition.