Investigation of Acute Toxicity of Methanolic Extract of Root of Grewia nervosa (Lour.) Panigrahi

Abstract

In this research work, the root of Grewia nervosa (Lour.) Panigrahi, one of Myanmar indigenous medicinal plants was selected for chemical analysis. The roots of G. nervosa (Lour.) Panigrahi (Myanmar name-Mya yar) were collected from Pyin Oo Lwin Township, Mandalay Region, Myanmar. The sample was cut into small pieces and dried in the air for about four weeks. Furthermore, the acute toxicity study on methanol extract of the root of G. nervosa (Lour.) Panigrahi was done by OECD guideline 425 (Organization for Economic Co-operation and Development) at Pharmacology Research Division, Department of Medical Research (Pyin Oo Lwin Branch), Mandalay Region, Upper Myanmar.