Relationship of Changes in Blood-Glucose Level with Albuminuria in Diabetic Patients Reporting in Civil Hospital-Karachi

Abstract

Objective: RELATIONSHIP OF CHANGES IN BLOOD-GLUCOSE LEVEL WITH ALBUMINURIA IN DIABETIC PATIENTS REPORTING IN CIVIL HOSPITAL-KARACHI

Participants and Method: It was a questionnaire based study conducted during the period of September 2015 till February 2016. In this study all data was collected by the co-investigators during a period of 1^stSeptember 2015to 29^th February 2016,300 patients were selected on the basis of internationally used equations used to calculate the sample size, and in the end data was analyzed by using SPSS 20.0 version.

Results: This study shows that as the duration of diagnosed diabetes increases the rate of RBS becoming uncontrolled increases directly like,   62.8% of individuals with duration of 20 years or more have a Random Blood Glucose level(RBS) of 301-400 mg/dl as compared to  22.1% of individuals with duration of Less than 5years. Also it shows that as the duration of diabetes increases the level of urine albumin increases like,  3.9% of individuals with diagnosis of diabetes for less than 5 years have urinary albumin level of >300mcg/mg of Creatinine , which reaches up to 82% in case when duration reaches 20 years or more, Also this study shows that as the level of RBS increases the level of urine creatinine increases exponentially, showing that as the duration of Diabetes increases the chances of nephropathy increases greatly

Conclusion: This study shows that as the duration of diabetes and level of RBS increases the chances for nephropathy increases exponentially so in order to reduce the risk of Diabetic Nephropathy (which is very much common in our society) doctors has to counsel their patients about the diabetes, its risk ,and most importantly its complications as by doing this we can control the complications of diabetes like nephropathy , ultimately reducing the ratio of mortalities and morbidities caused by the silent killer of the society, ‘THE DIABETES’ 

MesH words: Relationship; Diabetes; Nephropathy; Glucose level; Karachi.