The radioprotective nature of MRN-100 on Nile Tilapa (Oreochromis niloticus) under γ-radiation-Induction

Heba Allah M. Elbaghdady


Iron is an element that exists in various forms and compositions based on the overall electron charge on Fe-. Relevantly, one of the existent compounds derived from the ferrates group are the hydro ferrates and inclusively encompasses the MRN-100 ionic based compound. MRN-100 is a potent and chemically stable antioxidant compound derived from bivalent and trivalent ferrates (Fe2+/Fe3+). Potently, the experiment done was factually based on the concept of ionization radiation and the effects rendered on tissue. An analysis and examination of the defensive influence of MRN-100 counter to γ-radiation-induced lethality and reparation to hematopoietic tissues in fish species-Nile tilapia of interest. The modules of the experiment included specimen samples of 216 Nile tilapia (Oreochromis niloticus) equally divided between groups. Group 1 was configured as a control, Group 2 induced to γ-radiation (single dose of 15 Gy), Group 3 and 4 were ethologically pre-treated with doses of 1 ml of MRN-100 per litre of water and 3 ml/L in water for a period of 1 week, and then exposed to radiation, while continuing to receive MRN-100 for 1 week and 4 weeks respectively. The current study discussed parametric analysis of biochemical components in blood serum as well as lipid peroxidation in muscular tissue versus γ-radiation-Induction and MRN-100 effect on radioprotective ability. Conclusion is made that MRN-100 is viably a radioprotective agent in ichthyes/Pisces and validly can be used as a counteract for ionization radiation.

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