Synthesis and Identification of Some New Schiff Bases Complexes and Study of Their Biological Activity

Abstract

Schiff bases are adaptable ligands which are synthesized from the condensation of essential amines with carbonyl gatherings. These mixes are essential in medicinal and pharmaceutical fields in light of their wide range of biological activities. The greater part of them show biological activities such as antibacterial, antifungal as well as antitumor action. Move metal edifices got from the Schiff base ligands with biological action have been broadly contemplated. This audit abridges the combination and biological activities of Schiff bases and its buildings. Two buildings of Co(II) and Cu(II) with Schiff base got from o-phenylenediamine and 2-hydcoxyacetophonone have been synthesized by condensation in acidic medium. The synthesized edifices were examined utilizing distinctive physical techniques such as natural investigation (C, H and N), infrared, electronic and atomic attractive resonance spectroscopes. The geometrical structures of the synthesized edifices have been distinguished. The antibacterial movement of the Schiff base and their edifices have been additionally examined, showing that the buildings were of more antibacterial action than the free Schiff bases.