Study of Thyroid Dysfunction in Patients with Chronic Kidney Disease

Abstract

Chronic Kidney Disease is a worldwide health problem with an increasing incidence and prevalence. Abnormalities in the structure and function of the thyroid gland and in the metabolism and plasma concentration of thyroid hormones are common in patients with CKD. In view of variability of thyroid profile in CKD patients in previous studies, a prospective study of various thyroid function has been undertaken to establish a correlation if any between thyroid dysfunction and severity of renal diseases. Total number of 210patients with Chronic Kidney Disease fulfilling the criteria for CKD who were admitted in Department of Medicine, MGM Aurangabad, tertiary care hospital, during the period of May 2014-May 2016 were selected in this study. The result showed that out of the 210 patients with CKD 60 patients had thyroid dysfunction which accounted for 28.57%. Prevalence of hypothyroidism was 28.57%.The most common thyroid derangement was low T3. The number of patients with hypothyroidism progressively increased with the severity of renal failure.