Association between serum uric acid level & metabolic syndrome in patients of a tertiary care Centre

Abstract

Introduction: Elevated uric acid is a common feature of metabolic syndrome (MetS) that includes risk factors like hypertension, obesity, dyslipidaemia and insulin resistance (IR).

Aims &Objectives: The study was conducted to detect any association between uric acid level and metabolic syndrome and its gender dependence.

Materials & Methods: 50 male and 50 female obese participants with suspected metabolic syndrome included in hospital based cross sectional study to estimate their triglycerides, total cholesterol, fasting plasma glucose, HDL-cholesterol, LDL-cholesterol, uric Acid, ALT, AST  and also the anthropometric measurements like weight, height, waist circumference(WC),systolic blood pressure (SBP), diastolic blood pressure (DBP) were determined.

Results: Results showed that Total Cholesterol, Triglycerides & HDL-C are significantly correlated with increased uric acid level for both participants of either gender. However, FPG positively correlated only in cases of males.

Conclusion: The findings suggest that there is a significant correlation between metabolic syndrome and uric acid & preponderance in males compared to females