Hemostatic Parameters Of Blood In Patients With Chronic Generalized Parodontitis Associated With A Metabolic Syndrome

Abstract

The purpose of this study is to assess hemostatic blood counts in patients with chronic generalized periodontitis associated metabolic syndrome. Twelve practically healthy persons and 72 patients with CGP of medium degree were examined. Of these, 24 patients without concomitant diseases; 48 patients - with CHC associated with MS. The anticoagulant and fibrinolytic activity of vascular endothelium, the content of endothelin I and homocysteine in blood serum were studied. It was found that the increase in the time of HAGEMAN-dependent fibrinolysis and a decrease in fibrinolytic endothelial activity, as well as an increase in endothelin-I, which may be due to the activation of oxidative stress in endothelial cells in this pathology.