Isolation And Characterization Of Phytoconstituents From Fruits Of Aphanamixis Polystachya

Abstract

The meliaceaeous plants are rich source of limuloids and used as pesticide in agriculture. Aphanamixis polystachya R.N. Parker (Wall.) belongs to the family Meliaceae and it is a traditional plantnative to Asia, especially China and India. It is extensively used in folklore medicine of Bangladesh, for the treatment of various ailments like in liver and spleen disorders, tumors, ulcer, dyspepsia, intestinal worms, skin diseases, leprosy, diabetes, eye diseases, jaundice, hemorrhoids, burning sensation, arthritis and leucorrhoea. According to previous studies, A.polystachya has been extensively investigated since the 1960s because of the anticancer, antimicrobial and antifungal, anti-inflammatory, anti-oxidant, anti-diabetic, insecticidal and hepato protective properties of the plant extracts. A. polystachya well known source of limonoids and terpenoids with the wide range of biological activity. A.polystachya have led to the isolation of many structurally active constituents like terpenoids and limuloids with a pharmacological properties such as anti-feed ant, insecticidal and antioxidant activities. In our present study Photochemical investigation of fruits of hexane extract of Aphanamixispolystachya led to isolation of active constituents. The resulted active constituents were determined on the basis of HRMS, IR, 1D and 2D NMR data.